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Supplement Godfather

Don Gauvreau MSc, CSCS
Don Gauvreau, A.K.A. The Supplement Godfather, is one of the leading researchers and product formulators in the sports supplement industry.
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D-Aspartic Acid And Estrogen

Q. Do I need an anti-aromatase if I’m on D-aspartic acid?

A. Yes, I think it’s a good idea. The studies conducted on d-aspartic acid (DAA) measured not only the effects of DAA on testosterone release but also its effects on estrogen and progesterone secretion. Although there wasn’t a significant change in estrogen secretion, progesterone release did increase, and that’s not really a good thing! Just like estrogen, progesterone is predominantly a “female” hormone and is involved in the biosynthesis of estrogen. But there is some good news here. Before progesterone can be transformed into estrogen, it has to be converted to androstenedione. Once it’s converted into androstenedione it’s left with two final conversion pathways: estrogen or testosterone. In order for androstenedione to be converted to estrogen, the aromatase enzyme is needed. So that’s why it’s a good idea to use an effective anti-aromatase compound. By doing so, any extra circulating androstenedione won’t be converted into estrogen and instead would be converted back into testosterone. Clearly, this is a much better situation. Some of the best natural anti-aromatase compounds are resveratrol, hesperidin, and apigenin. And one of the newest anti-aromatase compounds that has been getting a lot of attention lately is a plant called Bulbine natalensis. It was recently discovered by researchers in South Africa. The results from a study just published in the journal Pharmaceutical Biology showed that treatment with a special strain of bulbine (only grown in South Africa) has very powerful anti-aromatase effects. In fact, it had such powerful anti-aromatase effects that it reduced estrogen levels by an incredible 35 percent! This in turn caused a big spike in test levels (about a 345 percent increase from baseline!)

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