Supplement Godfather
Don Gauvreau
MSc, CSCS
Don Gauvreau, A.K.A. The Supplement Godfather, is one of the leading researchers and product formulators in the sports supplement industry.
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The lowdown on Agmatine Sulfate
Q: Agmatine sulfate is appearing in a lot of supplements. Can you give me the lowdown on this ingredient?
A: I’ll start out by saying this: There’s very little human research on agmatine supplementation to date. At present, I’m only aware of one published human study. That being said, agmatine could turn out to be a very valuable supplement based on the findings of several in vitro and animal studies. Agmatine is a byproduct of the amino acid arginine and is produced through a process called decarboxylation. Essentially, agmatine is arginine with the carboxylic acid end removed.
Agmatine has been studied for a wide variety of properties and effects. Agmatine can help modulate nitric oxide synthase to potentially support muscle pumps! Research also suggests that agmatine may act on hormones such as luteinizing hormone (LH) and growth hormone (GH). Agmatine may also provide antioxidant and nootropic support.
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