Sports Nutrition Insider
What Is A Muscle Biopsy
Q: I heard some guys talking about physiology research and they keep mentioning a muscle biopsy. What is a muscle biopsy and is it safe to get one done?
A: Good question! A muscle biopsy is a very safe procedure, preformed by a medical doctor or a specialist that carries little risk for the patient. It is a valuable medical procedure that is used to identify conditions such as metabolic defects of the muscle, muscular disorders and infections that affect the muscles. However, it is also a very useful tool during dietary research to identify changes in the muscle following the addition of training and/or nutritional intervention. A muscle biopsy is a minor surgical procedure that involves making an incision in the skin (which is first numbed by local anaesthetic) and removing a few small pieces of the underlying muscle for chemical analysis. A needle is inserted into the muscle, usually while the patient is awake, where a small piece of tissue remains in the needle. During the biopsy, there is usually minimal or no discomfort. Patients may feel some pressure or ‘tugging sensations’. The risks are very small, but may include slight bruising and bleeding. Most subjects are back to regular activity within 24 hours.